Acta Univ. Agric. Silvic. Mendelianae Brun. 2012, 60(3), 125-132 | DOI: 10.11118/actaun201260030125
Compositions of polyphenols in wild chive, meadow salsify, garden sorrel and ag yoncha and their anti-proliferative effect
- 1 Institut zdravotnických studií, Ústav porodní asistence, Fakulta humanitních studií, Univerzita Tomáše Bati ve Zlíně, Mostní 5139, 760 01 Zlín, Česká republika
- 2 Centrum polymerních materiálů - Fakulta technologická, Centrum polymerních systémů, Univerzita Tomáše Bati ve Zlíně, nám. T. G. Masaryka 275, 762 72 Zlín, Česká republika
- 3 Ústav technologie a mikrobiologie potravin, Fakulta technologická, Univerzita Tomáše Bati ve Zlíně, nám. T. G. Masaryka 5555, 762 72 Zlín, Česká republika
- 4 Centrum polymerních materiálů - Fakulta technologická, Centrum polymerních systémů, Univerzita Tomáše Bati ve Zlíně. nám. T. G. Masaryka 5555, 760 05 Zlín, Česká republika
During past decades a lot of experimental studies shown that polyphenols have anti-carcinogenic properties have been published. Their antioxidant and tumour arresting effects have been demonstrated using both in vitro and in vivo studies many times. Aim of the present study was to investigate the content of polyphenols in edible flowers of Ag yoncha, Wild chive, Meadow salsify and Garden sorrel and their effect on proliferation activity of human hepatocellular carcinoma cells which has not been studied yet. Anti-proliferative effect was evaluated in vitro using following concentrations of polyphenols 100, 75, 50 and 25μg/ml. Also, phenolic composition was determined by the high performance liquid chromatography. The present results indicate that even low concentrations of edible flowers' polyphenols inhibited cell proliferation significantly. This effect was observed at all studied edible flowers extracts and was independent on the compositions of individual polyphenols. Results indicate possible employment of studied edible flowers for prevention as well as for treatment of cancers.
Keywords: proliferation, Ag yoncha, Wild chive, Meadow salsify, Garden sorrel, polyphenols, HepG2
Grants and funding:
This article was created with the support of Operational Program Research and Development for Innovations co-funded by the European Regional Development Fund (ERDF) and national budget of Czech Republic, within the framework of project Centre of Polymer Systems (reg. number: CZ.1.05/2.1.00/03.0111). Author Z. Kuceková thanks to supporting by the internal grant of TBU in Zlin No. IGA/FT/2012/029 funded from there sources of specific uiversity research.
Received: May 12, 2011; Published: August 28, 2013 Show citation
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