Acta Univ. Agric. Silvic. Mendelianae Brun. 2023, 71(2), 89-96 | DOI: 10.11118/actaun.2023.007

Stability Evaluation of Royal Jelly Gel

Putri Anugrah Rizki1, 2, Desak Gede Budi Krisnamurti3, Mirta Hediyati Reksodiputro4, Siti Farida3, Trimartani Koento2, Lisnawati Rachmadi5, Puspita Eka Wuyung5, 6, Heri Wibowo7, Shinta Fitri Boesoirie8
1 Doctoral Program in Medical Sciences Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia
2 Departement of ENT, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Banten, 15419, Indonesia
3 Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia
4 Departement of ENT, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia
5 Departement of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia
6 Animal Research Facility, Indonesian Medical Education and Research Institute Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia
7 Departement of Parasitology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia
8 Departement of ENT, Faculty of Medicine Universitas Padjajaran, Jawa Barat, 45363, Indonesia

Scars that occur in surgical wounds are still a health problem worldwide. Excessive scarring significantly affects the patientʹs quality of life, both physically and psychologically, and can also cause pain, pruritus, and contractures and cost a considerable amount of money. Therefore, it is essential to find dressings that improve a patient's prognosis. Topical therapy for treating scars is becoming popular because it is easy to use, convenient, non-invasive, and relatively inexpensive. However, no single therapy provides optimal results to eliminate hypertrophic scar formation. For most people in the world, herbs are easier to obtain because they are widely available at relatively affordable prices, so herbal therapy is still the main choice in wound healing management. Nowadays, the selection of natural ingredients such as Royal Jelly (RJ) has increased in popularity and is in demand by the public for improving the healing of surgical wounds. The study found that the flavonoid content in the sample was equivalent to quercetin and that the total phenol content in the royal jelly extract ranged from 1.41% to 1.66%. The stability test showed that the royal jelly was stable in different conditions for up to 28 days, with no significant changes observed in pH, color, smell, texture, or spreadability.

Keywords: scar, royal jelly, surgical wounds, dressing

Received: February 20, 2023; Revised: April 14, 2023; Accepted: April 17, 2023; Published: May 1, 2023  Show citation

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Rizki, P.A., Krisnamurti, D.G.B., Reksodiputro, M.H., Farida, S., Koento, T., Rachmadi, L., ... Boesoirie, S.F. (2023). Stability Evaluation of Royal Jelly Gel. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 71(2), 89-96. doi: 10.11118/actaun.2023.007
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