Acta Univ. Agric. Silvic. Mendelianae Brun. 2012, 60(5), 97-102 | DOI: 10.11118/actaun201260050097

Association analysis of interleukin-18 gene with performance traits in Czech Large White pigs

Pavla Chalupová1, T. Urban, A. Knoll
1 Ústav morfologie, fyziologie a genetiky zvířat a CEITEC MENDELU, Mendelova univerzita v Brně, Zemědělská 1, 613 00 Brno, Česká republika

This research focused on recently described MspI and VspI SNPs in interleukin-18 gene and their association with selected performance traits (backfat thickness; lean meat content, average daily gain from birth, average daily gain in test, breeding value for average daily gain, for lean meat content, for reproduction and total breeding value) in a population of 344 Czech Large White sows. Both SNPs were genotyped by PCR-RFLP. In this work, these polymorphisms were associated with backfat thickness and lean meat content. Animals with genotype AA (MspI SNP) had significantly (P < 0.05) lower backfat thickness and higher lean meat content (0.77 ± 0.02 and 62.16 ± 0.23, resp.) compared to GA (0.83 ± 0.02 and 61.40 ± 0.18, resp.). Animals with genotype AA (VspI SNP) had significantly (P < 0.05) lower lean meat content and higher backfat thickness (61.10 ± 0.36 and 0.85 ± 0.03, resp.) compared to GA (62.02 ± 0.16 and 0.77 ± 0.02, resp.). No association between IL-18 polymorphisms and other performance traits was found. Our study revealed that IL-18 could be candidate gene for backfat thickness and lean meat content in pigs.

Keywords: pig, IL-18, polymorphism, performance traits, association
Grants and funding:

This study was supported by the GAČR 523/09/0844 and realized in the European center of excellence "CEITEC - Central European Institute of Technology" supported by the project CZ.1.05/1.1.00/02.0068 from the European Regional Development Fund.

Received: May 3, 2012; Prepublished online: July 24, 2013; Published: July 30, 2013  Show citation

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Chalupová, P., Urban, T., & Knoll, A. (2012). Association analysis of interleukin-18 gene with performance traits in Czech Large White pigs. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 60(5), 97-102. doi: 10.11118/actaun201260050097
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