Acta Univ. Agric. Silvic. Mendelianae Brun. 2018, 66, 17-22
Published online 2018-02-28

Influence of Mycotoxins in Barley Monodiets on Growth Performance and Rats Liver Histology

Hana Dočkalová1, Pavel Horký1, Ladislav Zeman1, Ondřej Polák2, Jiří Skládanka1

1Department of Animal Nutrition and Forage Production, Faculty of Agronomy, Mendel University in Brno, Zemědělská 1, 613 00 Brno, Czech Republic
2Department of Crop Science, Breeding and Plant Medicine, Faculty of Agronomy, Mendel University in Brno, Zemědělská 1, 613 00 Brno, Czech Republic

The presence of mycotoxins in animal feed cause health disorders and can also contribute to other factors such as stress, lack of nutrition, infectious agents etc. The aim of this article was to study effect of feed ration contaminated with mycotoxins on liver histology and live weight of laboratory rats. 15 pieces of laboratory rats were divided into 3 groups (A, B, C). The rats in first group (A) fed with part of 30 % mycotoxin-contaminated barley, in second group (B were fed with 60 % and in control group (C) were fed without mycotoxin-contaminated barley. Content of deoxynivalenol (DON) was 9634 µg/kg and content of zearalenone (ZEN) was 2192 µg/kg. Barley monodietus were given rats in all groups to induce a nutritional imbalance. The aim of this study was to monitor the effect of mycotoxins and nutritional imbalances on weight gains and liver histology. The question is, “will the presence of mycotoxins in feed dose increase negative effect of a monodiets on health status?” No significant differences were found between the observed parameters. The presence of mycotoxins did not aggravate the negative effect of the monodiets on liver histology of the experimental rats.


The research was financially supported by the IGA FA Mendelu in Brno No. IP 031/2017.


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